Evaluating Pharmacokinetic/Pharmacodynamic Models Using the Posterior Predictive Check
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- 1 January 2001
- journal article
- Published by Springer Nature in Journal of Pharmacokinetics and Pharmacodynamics
- Vol. 28 (2) , 171-192
- https://doi.org/10.1023/a:1011555016423
Abstract
The posterior predictive check (PPC) is a model evaluation tool. It assigns a value (p PPC) to the probability that the value of a given statistic computed from data arising under an analysis model...Keywords
This publication has 5 references indexed in Scilit:
- Pharmacokinetic/Pharmacodynamic Modeling in Drug DevelopmentAnnual Review of Pharmacology and Toxicology, 2000
- A Population Pharmacokinetic–Pharmacodynamic Analysis of Repeated Measures Time-to-Event Pharmacodynamic Responses: The Antiemetic Effect of OndansetronJournal of Pharmacokinetics and Biopharmaceutics, 1999
- A Markov mixed effect regression model for drug complianceStatistics in Medicine, 1998
- A population pharmacokinetic model for docetaxel (Taxotere®): Model building and validationJournal of Pharmacokinetics and Biopharmaceutics, 1996
- The analysis of repeated‐measures data on schizophrenic reaction times using mixture modelsStatistics in Medicine, 1995