An Investigation into Some Pharmaceutical Interactions by Differential Scanning Calorimetry
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 7 (6) , 675-682
- https://doi.org/10.3109/03639048109055691
Abstract
Differential scanning calorimetry has been used to investigate the interactions between the drugs indomethacin and chlorproparaide with some tablet excipients, and also between the excipients themselves. Chlorpropamide was found to interact with both sodium starch glycolate and magnesium stearate, indomethacin with magnesium stearate and the tablet binder polyethylene glycol 6000 with microfine cellulose.Keywords
This publication has 7 references indexed in Scilit:
- Oxytetracycline tablet formulations: preformulation stability screening using differential thermal analysisJournal of Pharmacy and Pharmacology, 1977
- Phase equilibria and stability characteristics of chlorpropamide-urea solid dispersionsJournal of Pharmacy and Pharmacology, 1977
- Kinetics and mechanism of penicillin aminolysis involved in penicillin allergyJournal of Pharmacy and Pharmacology, 1975
- Melting of low molecular weight poly(ethylene oxide)Polymer, 1972
- Application of Differential Thermal Analysis to Compatibility and Stability Problems in Penicillin-Stearic Acid MixturesJournal of Pharmaceutical Sciences, 1969
- Thermal analysis and calorimetry of some fatty acid sodium soapsJournal of Oil & Fat Industries, 1968
- Characterization of Starch and Related Polysaccharides by Differential Thermal AnalysisAnalytical Chemistry, 1956