STUDIES ON ISO-AGGLUTININS IN THE BLOOD OF THE NEW-BORN

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Abstract
Transfusion of blood has become such a specific curative measure in hemorrhagic disease of the new-born and in traumatic or accidental hemorrhages in the new-born occurring during delivery that the practical application of this work will become evident at once. Some observers have stated that iso-agglutinins and isohemolysins are not present in the blood of the new-born and, hence it is unnecessary to test for compatibility of the bloods when the mother acts as donor for her offspring. On the other hand, others assert that both iso-agglutinins and isohemolysins are present in the blood of the new-born, even in that of premature infants, before birth, and that transfusion without compatibility tests may prove disastrous. The latter opinion is the one prevailing. It is on account of this variation in opinions that the present study attempts to verify either contention. One hundred mothers and their respective new-born babies were grouped (Moss'

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