The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules
Open Access
- 7 August 2007
- journal article
- Published by Springer Nature in BMC Biology
- Vol. 5 (1) , 33
- https://doi.org/10.1186/1741-7007-5-33
Abstract
Impairment of cilia and flagella function underlies a growing number of human genetic diseases. Mutations in hydin in hy3 mice cause lethal communicating hydrocephalus with early onset. Hydin was recently identified as an axonemal protein; however, its function is as yet unknown.Keywords
This publication has 55 references indexed in Scilit:
- Chlamydomonas reinhardtiihydin is a central pair protein required for flagellar motilityThe Journal of cell biology, 2007
- Flagellar Motility Contributes to Cytokinesis inTrypanosoma bruceiand Is Modulated by an Evolutionarily Conserved Dynein Regulatory SystemEukaryotic Cell, 2006
- Deficiency of SPAG16L Causes Male Infertility Associated with Impaired Sperm Motility1Biology of Reproduction, 2006
- Flagellar motility is required for the viability of the bloodstream trypanosomeNature, 2006
- A novel domain suggests a ciliary function for ASPM, a brain size determining geneBioinformatics, 2006
- Proteomic analysis of a eukaryotic ciliumThe Journal of cell biology, 2005
- Robust Method for Proteome Analysis by MS/MS Using an Entire Translated Genome: Demonstration on the Ciliome ofTetrahymenathermophilaJournal of Proteome Research, 2005
- Loss of the Tg737 protein results in skeletal patterning defectsDevelopmental Dynamics, 2003
- A Sperm-Associated WD Repeat Protein Orthologous to Chlamydomonas PF20 Associates with Spag6, the Mammalian Orthologue of Chlamydomonas PF16Molecular and Cellular Biology, 2002
- Congenital Hydrocephalus: Treatment in uteroFetal Diagnosis and Therapy, 1988