QUANTITATIVE STUDIES OF Gm ALLOTYPES:V. SIMULTANEOUS PRESENCE OF LATENT Gm ALLOTYPES AND DEFICIENT Gm GENES IN A FAMILY WITH HYPOGAMMAGLOBULINAEMIC PROBANDS
- 2 April 1980
- journal article
- Published by Wiley in International Journal of Immunogenetics
- Vol. 7 (2) , 123-135
- https://doi.org/10.1111/j.1744-313x.1980.tb00714.x
Abstract
A study of Gm allotypes in a Caucasoid family with hypogammaglobulinaemic probands, showed qualitative (unexpected or lacking Gm allotypes) and quantitative (increased or decreased Gm contents) abnormalities in many relatives. Part of these observations can be most probably accounted for by inheritance of a Gm1,17;5,28 haplotype, not described in Caucasians yet, and by an in vivo expression of latent Gm genes.Keywords
This publication has 35 references indexed in Scilit:
- An amino acid substitution in the γ1 chain of human immunoglobulin g associated with the Gm(2) allotypeMolecular Immunology, 1979
- Isolation and characterization of IgG molecules expressing latent group b allotypes from pedigreed b4b4 rabbits.The Journal of Experimental Medicine, 1978
- QUANTITATIVE STUDIES OF Gm ALLOTYPES II. G1m(1), G3m(5) AND G3m(21) IN SERA FROM HEALTHY CAUCASOID BLOOD DONORS, AND IN A FAMILY WITH THE INHERITANCE OF A GENE RESPONSIBLE FOR A WEAK Gm1, 17, 21, HAPLOTYPEInternational Journal of Immunogenetics, 1977
- HUMAN IgG3 ALLOTYPES, WITH SPECIAL REFERENCE TO A NEW ALLOTYPE RELATED TO G3m(g) (G3m21)International Journal of Immunogenetics, 1977
- Review of the notation for the allotypic and related markers of human immunoglobulinsEuropean Journal of Immunology, 1976
- An anti-immunoglobulin specificity in human multiple myeloma seraClinical Immunology and Immunopathology, 1975
- Familial occurrence of isolated IgA deficiency associated with antibodies to IgA. Evidence against a structural gene defectEuropean Journal of Immunology, 1974
- Genetic Control of Deficiencies in γG Subclasses observed among Families with HypogammaglobulinaemiaNature, 1970
- Regulatory Genes controlling the Synthesis of Heavy Chains of Human Immunoglobulin-GNature, 1967
- Immunochemical quantitation of antigens by single radial immunodiffusionImmunochemistry, 1965