Synthesis and Antibacterial Activity of 1‐β‐Methylcarbapenem Having a 1,3‐Diazabicyclo[3.3.0]octan‐4‐one Moiety
- 1 January 1996
- journal article
- research article
- Published by Wiley in Archiv der Pharmazie
- Vol. 329 (10) , 443-446
- https://doi.org/10.1002/ardp.19963291004
Abstract
The synthesis of new series of 1‐β‐methylcarbapenems having a 1,3‐diazabicyclo[3.3.0]octan‐4‐one moiety is described. Their in vitro antibacterial activities against both Gram‐positive and Gram negative bacteria are reported and the effect of the substituent on the bicyclic ring was investigated and was in agreement with findings from our previous studies.Keywords
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