Distribution and Properties of Na+, K+-ATPase in Human Post-Mortem Kidney and the Effects of Diuretics
- 1 March 1972
- journal article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 42 (3) , 265-275
- https://doi.org/10.1042/cs0420265
Abstract
1. Adenosine triphosphatase activity dependent on Mg2+ and activated by Na+ and K+ has been found in a microsomal fraction of homogenates of human postmortem kidneys. 2. Various characteristics of the enzyme system are described. 3. Activity is greater in the medulla than in the cortex. 4. Diuretic drugs inhibit activity in vitro only at high concentrations.Keywords
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