Abstract
A case of cutaneous infection in a 25-year-old male caused byPaecilomyces variotii is described. Animal pathogenicity studies with normal and cortisone-treated mice revealed the predeliction ofP. variotii for skin and liver in both normal and cortisone-treated mice and for lungs and heart only in immunosuppressed mice. 5-fluorocytosine gave the best MIC value forP. variotii in vitro. This report documents for the first time thatP. variotii causes cutaneous infection.