Amino Alcohol Mediated Enantioselective Addition of 2-Phenylethynylzinc Bromide to Aldehydes

Abstract
Optically active secondary phenylalkynyl alcohols were obtained in good yields and selectivities via (-)-N-methyl-ephedrine lithium salt mediated addition of 2-phenylethynylzinc bromide to alkyl and aryl aldehydes.

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