The Effect of Systemic Griseofulvin Pre-Treatment on Invasion of Bracken Prothalli by Botrytis cinerea

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Abstract
Griseofulvin pre-treatment of bracken (Pteridium aquilinum) prothalli reduces their susceptibility to invasion by Botrytis cinerea. The number of infection pegs successfully penetrating cell walls is reduced and the size of lesions, where penetration is achieved, is much reduced. This is partly attributed to reduction in fungal growth-rate by free griseofulvin, but there is also a change in host cell-wall reaction to infection. The general appearance of lesions in griseofulvin-treated prothalli is similar to that of lesions developing on naturally resistant clones of prothalli. Griseofulvin treatment has no effect on the susceptibility of prothalli to invasion by Pytkium debaryamtm.

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