Allergy to Laboratory Animals: Characterization and Source of Two Major Mouse Allergens, Ag 1 and Ag 3

Abstract
Using quantitative immunoelectrophoretic methods, two major allergenic components, Ag 1 and Ag 3, have been identified in extracts of mouse dust. Both antigens were of similar electrophoretic mobility and molecular weight (20–25 kilodaltons). However, Ag 1 proved to be antigenically identical to mouse urinary prealbumin, whilst Ag 3 was shown immunohistochemically to be present within the hair follicle and on the stratum corneum.

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