β-Turn-driven early evolution: The genetic code and biosynthesis pathways
- 1 May 1987
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 25 (1) , 15-19
- https://doi.org/10.1007/bf02100036
Abstract
The physicochemical properties of β-turns suggest their biological importance prior to the formation of the genetic code. These properties include ones potentially affecting the preference for eitherl- ord-amino acids. The abundance of certain amino acids in β-turns is correlated with their assignment to a small, well-defined part of the genetic code and with their role as metabolic precursors for other amino acids. It is proposed that in the prebiotic environment, β-turns became objects of selection that influenced the evolution of the genetic code and biosynthetic pathways for amino acids.Keywords
This publication has 20 references indexed in Scilit:
- Coordinating properties of the amide bond. Stability and structure of metal ion complexes of peptides and related ligandsChemical Reviews, 1982
- Reasons for the occurrence of the twenty coded protein amino acidsJournal of Molecular Evolution, 1981
- Intramolecularly Hydrogen-Bonded Peptide ConformationCritical Reviews in Biochemistry, 1980
- Calcium binding by troponin-C and homologs is correlated with the position and linear density of “β-turn forming” residuesJournal of Theoretical Biology, 1979
- Prediction of the Secondary Structure of Proteins from their Amino Acid SequencePublished by Wiley ,1979
- β structures of alternating polypeptides and their possible prebiotic significanceNature, 1975
- Chain reversals in proteinsBiochimica et Biophysica Acta (BBA) - Protein Structure, 1973
- Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide unitsBiopolymers, 1968
- Thermal Synthesis of Natural Amino-Acids from a Postulated Primitive Terrestrial AtmosphereNature, 1964
- THE ORIGIN OF OPTICAL ACTIVITYAnnals of the New York Academy of Sciences, 1957