Transcriptome Analysis of the Response of Pseudomonas aeruginosa to Hydrogen Peroxide
Open Access
- 1 January 2004
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 186 (1) , 248-252
- https://doi.org/10.1128/jb.186.1.248-252.2004
Abstract
Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H2O2 and untreated controls. The data indicate that the early response of P. aeruginosa to H2O2 consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.Keywords
This publication has 39 references indexed in Scilit:
- GeneChip Expression Analysis of the Response of Pseudomonas aeruginosa to Paraquat-Induced Superoxide StressGenome Letters, 2002
- Genome sequence of the plant pathogen Ralstonia solanacearumNature, 2002
- DNA Microarray-Mediated Transcriptional Profiling of the Escherichia coli Response to Hydrogen PeroxideJournal of Bacteriology, 2001
- Genetic and Physiological Characterization of ohr , Encoding a Protein Involved in Organic Hydroperoxide Resistance in Pseudomonas aeruginosaJournal of Bacteriology, 2001
- Role of the Pseudomonas aeruginosa oxyR-recG Operon in Oxidative Stress Defense and DNA Repair: OxyR-Dependent Regulation of katB-ankB , ahpB , and ahpC-ahpFJournal of Bacteriology, 2000
- Transcriptional Regulation of Glutaredoxin and Thioredoxin Pathways and Related Enzymes in Response to Oxidative StressJournal of Biological Chemistry, 2000
- ThePseudomonas aeruginosa fumcandsodaGenes Belong to an Iron-Responsive OperonBiochemical and Biophysical Research Communications, 1996
- Identification and characterization of a chromosomal virulence gene, vacJ, required for intercellular spreading of Shigella flexneriMolecular Microbiology, 1994
- Analysis of the DNA damage-mediated induction ofPsuedomonas putidaandPseudomonas aeruginosa lexAgenesFEMS Microbiology Letters, 1993
- Mechanism of specific LexA cleavage: Autodigestion and the role of RecA coproteaseBiochimie, 1991