ANTIGENIC ACTIVITY AND MOBILITY OF BOVINE PITUITARY HORMONES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 12  (1) , 59-68
Abstract
The antigenic activity and mobility of bovine pituitary hormones, follicle stimulating hormone (FSH), growth hormone (GH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), ACTH and melanophore stimulating hormone (MSH) were studied with the aid of agar gel diffusion and electrophoresis. MSH and ACTH were the only hormones not demonstrating antigenicity. Tests by electrophoresis showed gamma mobility of the pituitary hormones exhibiting antigenic activity. The observation of antigenic determinants exhibiting identity with immunoglobulins [Ig] suggests that the bovine pituitary gland houses Ig-like materials which may be precursors of the intact Ig molecule and the pituitary hormones.

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