A Ten-Year Study of Mycotic Infections in a Virginia General Hospital

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Abstract
This survey consisted of clinical records, autopsy protocols, and biopsy and culture reports of all patients with mycotic infections from the Medical College of Virginia (1400 beds) during a 10-year period from 1957 to 1966. A total of 134 patients was found to have mycotic infections. Of these, 69 were primary infections (51 %) and 65 were secondary (49%). The most common of the primary infections was histoplasmosis, while in the secondary infections candidiasis was the most common. Two cases of double infection were found. In 14 % of the cases, the disease was generalized. The respiratory system was involved in 58 % of the primary infections and 46% of the secondary infections. In 50% of the cases, the agent was identified in tissue sections. About 25 % of the cases were initially diagnosed by culture of the organism. The patients in both groups combined had a mortality rate of 15%. Among those with secondary fungal disease, 25% died of the initial illness unrelated to the mycotic infection.

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