Remarkable acceleration of a lipase-catalyzed reaction by a thiacrown ether additive: buffer-free highly regioselective partial hydrolysis of 4-acetoxy-2-methylbut-2-enyl acetate
- 1 January 1997
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 16,p. 2275-2278
- https://doi.org/10.1039/a702894f
Abstract
The reaction efficiency of the lipase-catalyzed partial hydrolysis of 4-acetoxy-2-methylbut-2-enyl acetate is greatly enhanced by the presence of 5 mol% of a thiacrown ether, particularly remarkable improvement being observed in CRL- and PCL-catalyzed reactions. 4-Hydroxy-2-methylbut-2-enyl acetate has thus been simply prepared by buffer-free lipase-catalyzed hydrolysis.Keywords
This publication has 0 references indexed in Scilit: