Subcellular Localization of the Methylcitric‐Acid‐Cycle Enzymes in Propionate Metabolism of Yarrowia Zipolytica
- 1 July 1982
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 125 (3) , 523-527
- https://doi.org/10.1111/j.1432-1033.1982.tb06713.x
Abstract
The subcellular localization of the 4 characteristic enzymes of the methylcitric acid cycle was studied with glucose-grown as well as n-alkane-grown cells of Y. lipolytica. Microsomes and peroxisomes showed no cycle enzyme activities. The 4 cycle enzymes were constitutively lcoalized in mitochondria, with the exception of the dual localization of the 4th enzyme, 2-methylisocitrate lyase, in mitochondria and cytoplasm, where the lyase may function to supply pyruvate (the end-product of the catabolism of the propionate residue) to various reactions.This publication has 29 references indexed in Scilit:
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