Abstract
In this issue of the Journal, Topol and the members of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group1 provide another critical piece of information that is destined to influence present trends in the management of acute myocardial infarction. Their multicenter randomized trial showed no additional improvement in ventricular function when balloon angioplasty carried out immediately after successful thrombolytic therapy was compared with a more elective procedure timed to be performed before hospital discharge. Both surprising and important, these findings provoke a desire to consider the background and the future of angioplasty in patients with acute infarction. . . .