The factor structure of the Wechsler Memory Scale-Revised was examined for 3 age groups (≤39, 40–55, ≥56) and three educational levels (< 12, 12. > 12) in a large group of patients (n = 434) referred for examination at two large medical centers. The subtests of the Wechsler Memory Scale Revised were subjected to principal components factor analyses. A separate set of analyses were performed that included the Verbal IQ and Performance IQ scores from the WAIS-R. Consistent with previous reports of age related changes in spatial function there appeared to be somewhat greater loading of nonverbal memory tests on verbal factors with increasing age. Inclusion of IQ scores appeared to have an affect on the content and relative prominence of the various factors in those subgroups formed on the basis of educational level. The results are discussed in regard to clinical use of the WMS-R and directions for future research.