Senescence-like changes induced by expression of p21Waf1/Cip1 in NIH3T3 cell line
- 1 September 2002
- journal article
- research article
- Published by Springer Nature in Cell Research
- Vol. 12 (3-4) , 229-233
- https://doi.org/10.1038/sj.cr.7290129
Abstract
Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis. It provides a single accessible source of information for both scientists and clinicians, keeping them up-to-date with advances in the field. It encompasses programmed cell death, cell death induced by toxic agents, differentiation and the interrelation of these with cell proliferation.Keywords
This publication has 16 references indexed in Scilit:
- Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditionsGenes & Development, 2001
- Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic RasOncogene, 1999
- p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53Oncogene, 1999
- Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicinOncogene, 1999
- Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4aCell, 1997
- A biomarker that identifies senescent human cells in culture and in aging skin in vivo.Proceedings of the National Academy of Sciences, 1995
- The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNANature, 1994
- Cloning of Senescent Cell-Derived Inhibitors of DNA Synthesis Using an Expression ScreenExperimental Cell Research, 1994
- The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesCell, 1993
- WAF1, a potential mediator of p53 tumor suppressionCell, 1993