Mek1/2 MAPK Kinases Are Essential for Mammalian Development, Homeostasis, and Raf-Induced Hyperplasia
Open Access
- 1 April 2007
- journal article
- Published by Elsevier in Developmental Cell
- Vol. 12 (4) , 615-629
- https://doi.org/10.1016/j.devcel.2007.03.009
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Ras‐induced spreading and wound closure in human epidermal keratinocytesThe FASEB Journal, 2005
- Mek1 Alters Epidermal Growth and DifferentiationCancer Research, 2004
- Mek2 Is Dispensable for Mouse Growth and DevelopmentMolecular and Cellular Biology, 2003
- NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasiaNature, 2003
- Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiationOncogene, 2002
- Constitutive Activation of Extracellular Signal-regulated Kinase 2 by Synergistic Point MutationsJournal of Biological Chemistry, 2001
- Targeted Genomic Disruption of H-ras and N-ras, Individually or in Combination, Reveals the Dispensability of Both Loci for Mouse Growth and DevelopmentMolecular and Cellular Biology, 2001
- Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesisOncogene, 2000
- Endothelial apoptosis in Braf-deficient miceNature Genetics, 1997
- Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase geneCurrent Biology, 1996