Biosynthetic relationship between the major matrix proteins of adrenal chromaffin granules
- 12 December 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 164 (2) , 383-388
- https://doi.org/10.1016/0014-5793(83)80322-6
Abstract
The matrix of the chromaffin granule contains a family of acidic proteins, collectively known as the chromogranins. It has been suggested that this family results protease action on the major component, chromogranin A. Evidence for this has now been obtained from in vitro translation of adrenal medullary messenger RNA and immunoprecipitation of translation products using an antiserum directed against chromogranin A, but which also recognises other chromogranins.Keywords
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