Resurgent Heterophil-Antibody Reaction after Mononucleosis

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Abstract
IN 1958 Bender1 presented the first report of anamnestic resurgence of the heterophil-antibody reaction after recovery from infectious mononucleosis. His observation has heretofore been unconfirmed. The purpose of this communication is to confirm his observations and briefly to discuss some of its implications. "Anamnestic resurgence" means return of characteristic heterophil antibodies after a patient has recovered from mononucleosis, unaccompanied by clinical features of the disease.In Bender's first case, a patient who had had mononucleosis eighty-five days previously became ill with "atypical pneumonia." Six days before the onset of pneumonia, the heterophil-antibody titer (which had been positive in a dilution . . .

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