Homology and concerted evolution at the α1 and α2 loci of human α-globin
- 1 March 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 290 (5801) , 26-29
- https://doi.org/10.1038/290026a0
Abstract
The identical structure of 2 racially distinct .alpha.1-globin alleles (from an Asian and a Caucasian) and the high degree of homology between the .alpha.1- and .alpha.2-globin loci indicate that mechanisms exist for suppression of allelic polymorphisms and for exchange of genetic information within the .alpha.-globin gene complex.This publication has 28 references indexed in Scilit:
- Cloning and complete nucleotide sequence of human 5'-alpha-globin gene.Proceedings of the National Academy of Sciences, 1980
- Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genesCell, 1980
- The structure of a human α-globin pseudogene and its relationship to α-globin gene duplicationCell, 1980
- The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletionsCell, 1980
- Rapid duplication and loss of genes coding for the alpha chains of hemoglobin.Proceedings of the National Academy of Sciences, 1980
- Polymorphisms of human γ-globin genes in Mediterranean populationsNature, 1979
- Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.Journal of Clinical Investigation, 1979
- The duplicated human alpha globin genes lie close together in cellular DNA.Proceedings of the National Academy of Sciences, 1978
- Localization of the human α-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assayCell, 1977
- THE ORGANIZATION, EXPRESSION, AND EVOLUTION OF ANTIBODY GENES AND OTHER MULTIGENE FAMILIESAnnual Review of Genetics, 1975