Perfume allergy due to oak moss and other lichens

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Abstract
During a period of 2.5 yr, of 7 of 2000 patients routinely tested revealed contact allergy to oak moss in perfumes. All reacted to a mixture of different lichens and to some specific lichen compounds. The sensitivity was probably induced by cosmetics containing lichen substances. The 3 compounds which caused reactions in all patients tested were atranorin, evernic and usnic acids. Three patients were photosensitive, but stronger reactions were elicited by prolonged contact during occlusion of the patches and complete protection against light, rather than by irradiation alone. The sensitizing capacity of the lichen compounds is apparently primarily of a contact rather than of a photocontact nature.

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