Physical Dependence on Morphine Fails to Develop During the Hibernating State
- 26 June 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 212 (4502) , 1527-1529
- https://doi.org/10.1126/science.7233241
Abstract
Physical dependence on morphine occurs in a typical fashion during the active state of the mammalian hibernator Citellus lateralis, but does not occur when morphine exposure is confined to the hibernating state. Morphine exposure during hibernation can produce stereotyped behavior, thus demonstrating partial responsiveness of the central nervous system to opioids during this natural state.This publication has 18 references indexed in Scilit:
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