An Efficient Method for Production and Storage of Unstable S-Nitrosothiols Under Mild and Heterogeneous Condition with Sodium Nitrite and Oxalic Acid Dihydrate
- 1 July 1999
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 29 (13) , 2277-2280
- https://doi.org/10.1080/00397919908086229
Abstract
Thiols can be readily converted to their corresponding nitrosothiols with a combination of oxalic acid and sodium nitrite in t-butanol at room temperature (26-30°C). The reaction mixture could be solidified with decreasing its temperature to, 15°C and was stored for several days without any destruction of the nitrosothiols.Keywords
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