[Evaluation of an optical immunoassay test for rapid detection of influenza A and B viral antigen].
- 1 January 1999
- journal article
- abstracts
- Published by The Japanese Association for Infectious Diseases in Kansenshogaku Zasshi
- Vol. 73 (12) , 1199-1204
- https://doi.org/10.11150/kansenshogakuzasshi1970.73.1199
Abstract
An optical immunoassay test, FLU OIA® (BIOSTAR, USA), was evaluated for the diagnosis of influenza viral infection. The reactivity of the FLU OIA test was evaluated using 42 influenza strains (25 human influenza A, 12 human influenza B, 2 swine influenza A and 3 avian influenza A strains). The FLU OIA test showed positive results for all influenza strains. There was no evidence that cross-reactivity occurred with non-influenza viruses. The detection limit of the FLU OIA test was found to be 3.0-6.5×104 pfu/assay for human influenza A and B strains. The sensitivity and specificity of the FLU OIA test compared to isolation in cell culture was 89.7% and 76.0% for testing of 54 nasopharyngeal aspirate specimens. The FLU OIA test is rapid and easy for the detection of influenza A and B viral antigen and provide a valuable tool for the rapid diagnosis of influenza viral infection.Keywords
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