CONTINUOUS AND QUANTITATIVE OBSERVATION OF PERMEABILITY CHANGES OF THE BLOOD-AQUEOUS BARRIER IN ALLERGIC INFLAMMATION OF THE EYE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 19  (2) , 169-175
Abstract
Permeability changes of the blood-aqueous barrier were studied in the eyes of rabbits subjected to immunologic inflammation. The changes were investigated by slit-lamp microphotometers. Leakage of fluorescein-labeled rabbit serum albumin into the anterior chamber was observed in eyes inflamed by reverse passive Arthus reactions. Permeability of the blood-aqueous barrier changed in biphasic pattern in allergic inflammation; the 1st phase began 5 min after the antigen challenge and lasted for 1 h, followed by the late phase at which the dye concentration reached a peak 2 h after the challenge and then gradually decreased.

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