Ventricular weight ratios of normal swine and from swine with pulmonic stenosis.

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Abstract
The ventricular weights of normal and experimentally hypertrophied swine hearts were studied. Right ventricular hypertrophy was induced by partially constricting the main pulmonary artery. A linear relationship and marked correlation was found to exist between the weight of the ventricles, its various components, and the body weight for normal swine. From the equations of the regression lines plotted between body weight and ventricular weight, it is possible to predict with reasonable accuracy the weight of the total ventricular mass of the heart and its various components in a normal animal of known body weight. Following partial stenosis of the main pulmonary artery, the right ventricular weight, central venous, and right cardiac pressures increased significantly in pigs with right heart failure.