Studies of Granuloma Inguinale IV. Growth Requirements of Donovania Granulomatis and its Relationship to the Natural Habitat of the Organism

Open Access
Publisher Website
Google Scholar
Abstract
Although Donovania granulomatis has been reported to grow only on material containing egg yolk, this organism may be grown when a low oxidation reduction potential is obtained by use of a thioglycollate medium, and when a factor in the enzymatic digest of bovine albumin or soya material is added. Acid hydrolysis destroys this 2d factor, believed to be a peptide. These findings, together with previously published serologic relationships between D. granulomatis and members of the Enterobacteriaceae indicate that the normal habitat of D. granulomatis is in the intestinal tract.