Volume of water-filled pores in the ethyl cellulose membrane and the permeability of microcapsules
- 1 July 1982
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 34 (7) , 411-414
- https://doi.org/10.1111/j.2042-7158.1982.tb04746.x
Abstract
The volume fraction of the water-filled pores in the microcapsule membranes was calculated and the values from 0.55 to 2.5% were obtained. Differential scanning calorimetry of aqueous suspensions of microcapsules showed no structured water present in the ethyl cellulose membranes. The temperature effect on the apparent diffusion coefficient of a drug was investigated and the apparent activation energy of diffusion was calculated.Keywords
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