Synthesis of indeno[1,2,3-ij]isoquinolines
- 1 January 1983
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 61 (1) , 7-13
- https://doi.org/10.1139/v83-002
Abstract
1-Methyl and 1-benzyl-1,2,3,10b-tetrahydro-5,6,8,9-tetramethoxyindeno[1,2,3-ij]isoquinoline have been synthesized from the corresponding 8-phenyl-3,4-dihydro-1(2H)isoquinolinones by treatment with POCl3 under Vilsmeier conditions followed by borohydride reduction. The isoquinolinones were prepared in six steps from 2-(2,3,4-trimethoxyphenyl)-4,4-dimethyl-2-oxazoline. This sequence of reactions provides a new route to dihydro and tetrahydroindeno[1,2,3-ij]isoquinolines.This publication has 1 reference indexed in Scilit:
- Synthesis of 8-phenyl-1,2,3,4-tetrahydroisoquinolinesThe Journal of Organic Chemistry, 1979