Effect of Thalidomide Treatment of Hens on Embryonic Development and Fertility.
- 1 July 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 113 (3) , 619-622
- https://doi.org/10.3181/00379727-113-28443
Abstract
Summary Thalidomide fed in total doses of 70, 140, 500 or 1700 mg per hen (daily dose of 2.5 mg, 5.0, 25 and 85 mg/kg/day) increased the number of infertile eggs, fertile eggs which failed to develop and deaths in early and late stages of development. Egg production was not affected. Thalidomide treatment did not lead to an increase in gross malformations of the embryo. The effect of the drug was apparent on embryological development in the hen for as long as 30 days after discontinuing the drug.Keywords
This publication has 4 references indexed in Scilit:
- Thalidomide: Effect upon Pregnancy in the Rhesus MonkeyScience, 1963
- Metabolic Deficiencies in Protozoa Induced by ThalidomideScience, 1963
- Absorption of Thalidomide in the RatExperimental Biology and Medicine, 1962
- A series of normal stages in the development of the chick embryoJournal of Morphology, 1951