Selective cyclooxygenase inhibitors: Novel 4-spiro 1,2-diarylcyclopentenes are potent and orally active cox-2 inhibitors
- 20 April 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 5 (8) , 867-872
- https://doi.org/10.1016/0960-894x(95)00131-c
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesionsPublished by Elsevier ,2002
- Selective Cyclooxygenase Inhibitors: Novel 1,2-Diarylcyclopentenes Are Potent and Orally Active COX-2 InhibitorsJournal of Medicinal Chemistry, 1994
- Platelet activation and arterial thrombosisThe Lancet, 1994
- A novel one-pot conversion of methyl sulfones to sulfonamidesTetrahedron Letters, 1994
- NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitroProstaglandins, 1994
- Gastrointestinal Damage Associated with the Use of Nonsteroidal Antiinflammatory DrugsNew England Journal of Medicine, 1992
- One-Pot Synthesis of α,β-Unsaturated KetonesSynthesis, 1991
- The synthesis and study of new selenium and tellurium heterocyclic π-donorsSynthetic Metals, 1987
- Aspirin Selectively Inhibits Prostaglandin Production in Human PlateletsNature New Biology, 1971
- Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like DrugsNature New Biology, 1971