Cooling-induced augmentation of the contractile response of the golden hamster tracheal muscle to substance P in-vitro
- 1 May 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 38 (5) , 403-405
- https://doi.org/10.1111/j.2042-7158.1986.tb04600.x
Abstract
The effect of temperature on the substance P‐induced contraction of the isolated tracheal strip‐chain preparation from the golden hamster has been examined. A decrease of bath temperature from 37 to 20°C augmented the contractile response of the trachea caused by substance P. Similar cooling‐induced augmentation was observed in the contractile responses to caffeine and carbachol, but not to fratassium chloride. The increased responsiveness with lowered temperature of the trachea to substance P may be due to the acceleration of Ca2+ release from an intracellular storage site.This publication has 12 references indexed in Scilit:
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