Serotonin Deficiency in Infancy as One Cause of a Mental Defect in Phenylketonuria
- 15 May 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3620) , 883-884
- https://doi.org/10.1126/science.144.3620.883
Abstract
Serotonin deficiency induced in newborn mice and maintained to adulthood resulted in reduced ability to learn a maze. The serotonin deficiency was produced by overloading with phenylalanine plus tyrosine (to cause phenylketonuria), by feeding of reserpine, and by feeding of chlorpromazine from birth to maturity.Keywords
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