Posaconazole Therapy of Disseminated Phaeohyphomycosis in a Murine Model
Open Access
- 1 June 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (6) , 2288-2291
- https://doi.org/10.1128/aac.48.6.2288-2291.2004
Abstract
Immunocompetent ( nu /+) and athymic ( nu / nu ) BALB/c mice were infected intravenously with Wangiella dermatitidis and treated with posaconazole. Posaconazole reduced the counts in tissues and prolonged survival. Of particular interest, posaconazole reduced the counts of this neurotropic pathogen in the brain.Keywords
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