Androgen Modulation of Adrenal Angiotensin Receptors
- 1 June 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 224 (4652) , 1009-1011
- https://doi.org/10.1126/science.6326265
Abstract
Several polar androgens increased the binding of angiotensin and its stimulation of aldosteronogenesis in bovine adrenal glomerulosa cells. The effect was seen only if the steroids were applied to the cells and then washed away. This phenomenon and the technique for demonstrating it may have implications for studies of receptor modulation and for clinical states in which responsiveness to angiotensin is increased.This publication has 22 references indexed in Scilit:
- Cholesteryl hemisuccinate alters membrane fluidity, angiotensin receptors, and responses in adrenal glomerulosa cellsLife Sciences, 1983
- 19-Hydroxyandrostenedione as a new hypertensinogenic agentThe Journal of Steroid Biochemistry and Molecular Biology, 1982
- Effect of the Membrane Lipid Environment on the Properties of Insulin ReceptorsDiabetes, 1981
- Steroids as potential modulators of angiotensin receptors in bovine adrenal glomerulosa and kidneySteroids, 1981
- Modulation of serotonergic receptors by exogenous cholesterol in the dog synaptosomal plasma membraneBiochemical Pharmacology, 1980
- Adrenal sensitivity to angiotensin II and undiscovered aldosterone stimulating factors in hypertensionJournal of Steroid Biochemistry, 1979
- Modulation of Transferrin Receptors in Bone Marrow Cells by Changes in Lipid FluidityBritish Journal of Haematology, 1979
- Increased Adrenal Sensitivity to Angiotensin II in Low-Renin Essential HypertensionJournal of Clinical Investigation, 1978
- Enhanced aldosterone response to angiotensin II in human hypertension.Circulation Research, 1976
- The Fluid Mosaic Model of the Structure of Cell MembranesScience, 1972