Incorporation in vivo of P32 from Condensed Phosphates
- 1 January 1959
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 100 (1) , 53-55
- https://doi.org/10.3181/00379727-100-24520
Abstract
P32 from trimetaphosphate and polymetaphosphate localizes preferentially in bone, particularly in actively growing areas. The metaphosphates are superior to NaH2P3204 as a P32 donor to bone, the extent depending upon experimental conditions. In particular, polymetaphosphate has a longer body retention and a higher bone-soft tissue ratio. The equivalent localization of p32 from NaH2P3204, trimetaphosphate and polymetaphosphate into the nuclei and mitochondria of liver cells is offered as evidence that the metaphosphates are enzymatically broken down to phosphates before incorporation.Keywords
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