Bacillus Diphtheriae

Open Access
Publisher Website
Google Scholar
Abstract
Summary: At least two distinct biologic groups of B. diphtheriae exist among virulent strains, as differentiated by the agglutination reaction. We were unable to confirm the contention, that group II toxin is not neutralized by standard antitoxin to the same extent as group I toxin. The results of the experiments presented, lead us to the conclusion that diphtheria antitoxin as produced by the injection of toxin obtained from group I strains, neutralized equally well the toxins produced by either group I or group II organisms. One, one and a half, and two units of standard antitoxin injected simultaneously with large doses of virulent cultures, protect guinea-pigs against both types of B. diphtheriae. We wish to acknowledge the courtesy of Drs. R. D. Meader, G. H. Robinson, and L. C. Havens, in supplying us with group II cultures.

This publication has 0 references indexed in Scilit: