CORRELATION OF HLA MATCHING WITH KIDNEY GRAFT SURVIVAL IN PATIENTS WITH OR WITHOUT CYCLOSPORINE TREATMENT
- 1 September 1985
- journal article
- research article
- Published by Wolters Kluwer Health in Transplantation
- Vol. 40 (3) , 240-242
- https://doi.org/10.1097/00007890-198509000-00003
Abstract
In a series of more than 8000 first cadaver transplants performed during a two-year period, 2198 recipients treated with cyclosporine had a higher graft survival rate (76±1% at 1 year) than 6392 recipients without cyclosporine (64±1%, PP<0.0001). Regardless of whether cyclosporine was used or not, grafts with 0 HLA-B,-DR incompatibilities had approximately 20% higher success rates at one year than grafts with 4 mismatches. A high (86±3%) graft survival rate was obtained in 161 cyclosporine-treated recipients with 0 HLA-B,-DR mismatches. Matching for the HLA-B and HLA-DR loci is shown to have an additive effect in cadaver kidney transplantation.This publication has 7 references indexed in Scilit:
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