Prevention of Breast Cancer: Focus on Chemoprevention

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Abstract
Breast cancer remains one of the “big killers” worldwide, even when the slight reduction in mortality figures of these last few years is taken into account. Given the current results of conventional cancer treatment, there are good reasons for improving the available preventive strategies and thus for exploring new ways in this direction. At present, prospects for breast cancer prevention are being developed in three main areas: (a) lifestyle, to study various risk factors, including delayed first pregnancy and number of pregnancies; (b) genetics, to understand the real importance of familial breast cancer and of genetic testing; and (c) chemoprevention, to identify agents potentially able to inhibit the development of invasive cancer.