Recent Developments in Nonspecific Inflammatory Bowel Disease

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Abstract
THE "nonspecific" inflammatory bowel diseases include ulcerative colitis and proctitis and Crohn's disease of the gastrointestinal tract. Their causes and precise relations remain obscure, and their designation as nonspecific reflects our continuing lack of knowledge of their pathogenesis.1 , 2 The incidence of the nonspecific inflammatory bowel diseases, especially of Crohn's disease, has increased worldwide,3 and they have emerged as one of the important biomedical problems of our time.*DefinitionsUlcerative colitis is a recurrent inflammatory and ulcerative disease of the colon and rectum, characterized clinically by rectal bleeding, diarrhea, cramping abdominal pain, anorexia, and weight loss. The diffuse tissue reaction (including . . .

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