Agranulocytosis Following Pyribenzamine

Abstract
THE effectiveness of Pyribenzamine (tripelennamine hydrochloride) in many allergic states and its apparent freedom from toxicity have led to its widespread use with little fear of serious reaction. Thus far only 1 case of depression of the granulocytic series after Pyribenzamine therapy has been reported.1 The following case is believed to represent agranulocytosis resulting from the use of Pyribenzamine over a period of five and a half weeks.Case ReportA 39-year-old housewife entered the hospital complaining of sore tongue and mouth of 3 days' duration. The past history included migraine headache since the menarche, for which she had frequently . . .