Oxidative Heterocyclization Using Diethyl Azodicarboxylate
- 1 January 1990
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1990 (11) , 1020-1023
- https://doi.org/10.1055/s-1990-27081
Abstract
The reactions of amidinothioureas, imidoylthioureas, thioacylamidines, O-methyl-1-aryl-2-thioisobiurets, and 1-aryl-isodithiobiurets with diethyl azodicarboxylate (DEAD, diethyl diazenedicarboxylate) gave the corresponding thiadiazoles by the oxidative cyclic S-N bond formation. Analogously, the oxidative cyclization of 2-phenyl-5-(1-methylthiosemicarbazido)-3(2H)-pyridazinones with DEAD provided 4-methyl-7-phenyl-4H-pyridazino[4,5-e] [1,3,4]-thiadiazin-8(7H)-ones.Keywords
This publication has 0 references indexed in Scilit: