INHIBITION OF FERTILITY IN MICE BY STEROID IMPLANTS
- 1 April 1965
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 48 (4) , 602-608
- https://doi.org/10.1530/acta.0.0480602
Abstract
Inhibition of fertility in female mice by steroid implants was studied. 19-Norprogesterone, 10% and 20% pellets, and testosterone, 15% and 45% pellets, were effective fertility inhibitors in female mice. Two important antifertility steroids, chlormadinone and 17[alpha]-acetoxypregn-4,6-diene-3,20-dione were only moderately effective. The present data on a relatively limited number of compounds indicate that the anti-fertility activity of progestational agents in normal female mice is a parameter independent of the basic progestationa! activity, anti-ovulatory activity and anti-estrogenic activity.Keywords
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- THE COMPARATIVE ANTILUTEINIZING POTENCY OF PROGESTERONE DERIVATIVES WITH OXIDATION AT C-11, C-21 AND C-17Endocrinology, 1957
- THE ANTILUTEINIZING POTENCY OF FIVE DERIVATIVES OF PROGESTERONEEndocrinology, 1956
- EXPERIMENTS WITH THE LOCAL ACTION OF OESTROGEN ON THE INTRASPLENIC OVARIAN GRAFTEndocrinology, 1950