Reduction of ischemic K+ loss and arrhythmias in rat hearts. Effect of glibenclamide, a sulfonylurea.
- 1 February 1990
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 66 (2) , 478-485
- https://doi.org/10.1161/01.res.66.2.478
Abstract
Glibenclamide, one of the antidiabetic sulfonylureas, is known to block ATP-dependent K+ channels. We used this drug to determine to what extent K+ loss from acutely ischemic myocardium is mediated...This publication has 47 references indexed in Scilit:
- Effects of diltiazem on early ischemic ventricular arrhythmiasJournal of Molecular and Cellular Cardiology, 1987
- Potassium efflux from the myocardium during hypoxia: role of lactate ionsCardiovascular Research, 1987
- Models for the study of arrhythmias in myocardial ischaemia and infarction: the use of the ratJournal of Molecular and Cellular Cardiology, 1987
- Intracellular ADP activates K+ channels that are inhibited by ATP in an insulin‐secreting cell lineFEBS Letters, 1986
- Free energy change of ATP-hydrolysis: a causal factor of early hypoxic failure of the myocardium?,Journal of Molecular and Cellular Cardiology, 1982
- Effect of acute coronary artery occlusion on local myocardial extracellular K+ activity in swine.Circulation, 1980
- Hypoxia increases potassium efflux from mammalian myocardiumCellular and Molecular Life Sciences, 1976
- Ion Alterations During Myocardial IschemiaCardiology, 1971
- Relationship between electrocardiogram and electrolytesAmerican Heart Journal, 1967
- Potassium and experimental coronary occlusionAmerican Heart Journal, 1966