Genetic Evidence That Protein Synthesis Is Required for the Circadian Clock of Neurospora
- 17 April 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 212 (4492) , 361-362
- https://doi.org/10.1126/science.212.4492.361
Abstract
Small doses of cycloheximide given at intervals (pulses) cause phase shifts of the circadian clock of Neurospora. The effects of this drug on the clock are mediated through its inhibition of protein synthesis, since two cycloheximide-resistant mutants whose 80S ribosomes are resistant to cycloheximide showed no phase shift after exposure to the durg.Keywords
This publication has 18 references indexed in Scilit:
- Assay and Characteristics of Circadian Rhythmicity in Liquid Cultures of Neurospora crassaPlant Physiology, 1981
- Spatial Distribution of Circadian Clock Phase in Aging Cultures of Neurospora crassaPlant Physiology, 1979
- Inhibition of the circadian rhythm of CO2 metabolism in Bryophyllum leaves by cycloheximide and dinitrophenolPlanta, 1979
- Phase shifting the circadian rhythm of neuronal activity in the isolated Aplysia eye with puromycin and cycloheximide. Electrophysiological and biochemical studies.The Journal of general physiology, 1976
- Evidence for a cycloheximide-sensitive component in the biological clock ofExperimental Cell Research, 1976
- The effect of different inhibitors of transcription and translation on the expression and control of circadian rhythm in individual cells of AcetabulariaExperimental Cell Research, 1975
- Cycloheximide Is Not a Specific Inhibitor of Protein Synthesis in VivoPlant Physiology, 1975
- Role of ribosomes in cycloheximide resistance of Neurospora mutantsMolecular Genetics and Genomics, 1973
- Direct inhibition of the uptake of proline by cycloheximideBiochemical and Biophysical Research Communications, 1973
- Selektion Actidion-resistenter Mutanten bei Neurospora crassa sowie ihre genetische und biochemische AnalyseMolecular Genetics and Genomics, 1970