Rôle du Système Nerveux Sur la Prolifération Cellulaire des Blastèmes de Régénération de Membre de Triton (Pleurodeles Waltlii Michah)

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Abstract
Cellular proliferation of epidermal and mesenchymal cells of denerved cone stage limb blastemas (P. waltlii Michah) was studied in vivo. The mitotic index and thymidine 3H incorporation (autoradiography following short-term (1 h) incubation and scintigraphy) showed that denervation causes a significant decrease in the cellular proliferation (.apprx. 70% four days after denervation). Denervation affects first the mesenchymal cells, the proliferation of epidermal cells declines later. These results are discussed in terms of cellular cycle.